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Prevnar Drug Interactions

A number of medications may cause drug interactions with Prevnar. For example, problems may occur if the vaccine is combined with anticoagulant medicines or immunosuppressants. If you are taking an immunosuppressant, you may not receive the full benefit of Prevnar. Also, caution should be taken when giving intramuscular injections (including Prevnar) to individuals taking anticoagulant medications.

An Overview of Prevnar Interactions

Prevnar® (pneumococcal conjugate vaccine) can potentially interact with a few medications or other vaccines. Some of the medicines or vaccines that may lead to drug interactions with Prevnar include:
 

 

 

 

    • Chemotherapy (as well as radiation treatment)
    • Corticosteroids, such as:

 

      • Betamethasone (Celestone®)
      • Cortisone
      • Dexamethasone (Decadron®)
      • Fludrocortisone (Florinef®)
      • Hydrocortisone (Cortef®)
      • Methylprednisolone (Depo-Medrol®, Medrol®)
      • Prednisolone (Pediapred®)
      • Prednisone
      • Triamcinolone (Kenalog®)

 

    • Cyclophosphamide (Cytoxan®)
    • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
    • Etanercept (Enbrel®)
    • Methotrexate (Rheumatrex®)
    • Mycophenolate (CellCept®)
    • Sirolimus (Rapamune®)
    • Tacrolimus (Prograf®).

 

(Prevnar Drug Interactions Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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